WebAug 5, 2014 · following exposure to PluriSIn#1, indicating that PluriSIn#2 works through a different mechanism of action (Fig. 1D). We therefore applied an unbiased toxicogenomic approach, in order to detect the gene expression changes induced by the compound. Following a 12-hour exposure of undifferentiated hPSCs to PluriSIn#2 (20 mm) or to control WebPluriSIn #1, induces ER stress, protein synthesis attenuation, and apoptosis in hPSCs. Close exami-nation identified this molecule as an inhibitor of stearoyl-coA desaturase (SCD1), the key enzyme in oleic acid biosynthesis, revealing a unique role for lipid metabolism in hPSCs. PluriSIn #1 was also cytotoxic to mouse blastocysts, indicating ...
PluriSIn #1 (NSC 14613) SCD1 inhibitor CAS# 91396-88-2
WebPlurisin is a gender that is complicated and influenced by being plural, a gender that a sum of all the genders within the plural, or a plurality gender.. Alternate Names. Plurisgenus; Plurisgender; Etymology "Pluris-" originates from "plural", and "-genus" originates from "genus", meaning "gender" in Latin. Definitions WebPluriSIn 1. ×. ×. Purity: >98.0% ... * Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact … mid america pullers association
APExBIO - PluriSIn #1 (NSC 14613) SCD1 inhibitor CAS# 91396 …
WebPluriSIn #1 is an inhibitor of the stearoyl-coA desaturase 1 (SCD1). Enzymes for Research, Diagnostic and Industrial Use WebNSC 14613 is a pluripotent cell-specific inhibitor (PluriSIn) that selectively eliminates human pluripotent stem cells (hPSCs) leaving a large array of progenitor and differentiated cells … Web在15种已确认的PluriSIn中,NSC 14613(亦称PluriSIn#1)是一种N-酰基苯肼的衍生物,与其它9种PluriSIn共享常见的苯基肼(PH-N[H,C]-NH)结构部分。 NSC14613也是 … mid-america psychiatric consultants llc