WebJun 10, 2024 · The phase 2 HCRN GU16-257 study enrolled 76 patients with cisplatin-eligible cT2 to T4aN0M0 clinically localized urothelial bladder cancer. Galsky noted that, “Due to COVID-19, there was some gap between enrollment of the first 64 patients and the remaining patients.” The median age was 69 years (range, 39-85) and 79% of patients … WebApr 6, 2024 · Therefore, bladder preservation therapies have emerged as an alternative treatment method. 29 In the phase II HCRN GU 16–257 study, 31 out of 64 MIBC patients who completed TURBT and four cycles of GC plus nivolumab achieved a clinical complete response and did not undergo cystectomy. 30 In the RETAIN BLADDER study, 26 MIBC …
Co-primary endpoint analysis of HCRN GU 16-257: Phase 2 trial of ...
WebMar 7, 2024 · Results from HCRN GU 16-257 suggest that clinical CR uniformly assessed and consistently defined does identify a patient population who has a favorable prognosis and could be targeted for a risk ... WebJun 22, 2024 · Findings from the phase 2 HCRN GU16-257 trial showed that combining transurethral resection of the bladder tumor (TURBT) with nivolumab (Opdivo) and chemotherapy is a promising bladder-sparing approach in patients with muscle-invasive bladder cancer (MIBC). 1. The study enrolled 76 patients with cisplatin-eligible cT2 to … law and order cast 2022 jamie ross
Encouraging Results Observed With Nivolumab-Based Regimen …
WebFeb 18, 2024 · The phase II clinical trial, known as HCRN GU16-260, involves front-line therapy with nivolumab and salvage therapy with nivolumab and ipilimumab. GU16-260 … WebImage for ASCO-GU 2024: HCRN GU14-188: Phase Ib/II study of neoadjuvant pembrolizumab and chemotherapy for T2-4aN0M0 urothelial cancer. - imageId : 301751 WebThe HCRN GU16-260 cohort A assessed the efficacy and safety of an initial nivolumab monotherapy followed by nivolumab and ipilimumab salvage approach in patients with treatment naïve clear cell RCC. ... Lombardi Comprehensive Cancer Center and the Scholl Professor and vice-chair of the Department of Medical Oncology at Georgetown … law and order cast anthony anderson