WebSep 5, 2014 · The theoretically calculated molecular weight of the monomeric TG2, including the C-terminal His-tag and GTP, was 78.52 kDa, and the experimental molecular weight from MALS was 78.57 kDa (0.84% fitting error), with a polydispersity of 1.0 . Based on our analysis using gel-filtration chromatography and MALS, we concluded that GTP … WebFor general laboratory use. Shipping: shipped on dry ice Storage Conditions: store at -20 °C Shelf Life: 6 months after date of delivery Molecular Formula: C 10 H 16 N 5 O 13 P 3 S (free acid) Molecular Weight: 539.25 g/mol (free acid) Exact Mass: 538.97 g/mol (free acid) CAS#: 94825-44-2 Purity: ≥ 90 % (HPLC), contains . 10 % GDP (HPLC). Form: solid …
Recombinant GTP exchange factor for ARFs 1 (grp-1) …
WebG proteins, also known as guanine nucleotide-binding proteins, are a family of proteins that act as molecular switches inside cells, and are involved in transmitting signals from a variety of stimuli outside a cell to its interior. Their activity is regulated by factors that control their ability to bind to and hydrolyze guanosine triphosphate (GTP) to guanosine … WebRab proteins represent the largest branch of the Ras-like small GTPase superfamily and there are 66 Rab genes in the human genome. They alternate between GTP- and GDP-bound states, which are facilitated by guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs), and function as molecular switches in regulation of … summit county ohio inmate roster pdf
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WebFor general laboratory use. Shipping: shipped on gel packs Storage Conditions: store at -20 °C Short term exposure (up to 1 week cumulative) to ambient temperature possible. Shelf Life: 12 months after date of delivery Molecular Formula: C 11 H 18 N 5 O 13 P 3 (free acid) Molecular Weight: 521.21 g/mol (free acid) Exact Mass: 521.01 g/mol (free acid) CAS#: … WebpH value: 8.1-8.5. GTP (1 μmol ≙ 13.7 A 252 units, pH 7.0): 100-110 mmol/L. GTP (HPLC): ≥98 area%. GDP (HPLC): ≤1.5 area%. GMP (HPLC): ≤0.5 area%. Functional transcription assay: Corresponds to specification. DNases/RNases: Negative. Nicking activity: Negative. Stability: At -15 to -25°C within specification range for 30 months. WebLow molecular weight GTP-binding proteins of the Rheb and Rag families are key regulators of the mTORC1 complex, but regulation of mTORC2 is poorly understood. Here, we report that Rac1, a member of the Rho family of GTPases, is a critical regulator of both mTORC1 and mTORC2 in response to growth-factor stimulation. Deletion of Rac1 in … summit county ohio highest elevation