Fezf2 神经元
Tīmeklis2010. gada 17. okt. · Rouaux and Arlotta show that expression of a single transcription factor, Fezf2, suffices to turn ventral forebrain progenitors committed to a striatal GABAergic fate into glutamatergic ... Tīmeklis2007. gada 10. jūl. · Transcription repressor. Required for the specification of corticospinal motor neurons and other subcerebral projection neurons. May play a role in layer and neuronal subtype-specific patterning of subcortical projections and axonal fasciculation. Controls the development of dendritic arborization and spines of large …
Fezf2 神经元
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Tīmeklis2013. gada 14. maijs · FEZF2 is readily expressed in normal tissues including upper respiratory epithelium, testis, brain and ovary tissues, as well as in immortalized nasopharyngeal epithelial cell line NP69, but it is completely silenced in NPC cell lines due to CpG methylation of its promoter, although no homozygous deletion of FEZF2 … Tīmeklis2024. gada 20. febr. · 神经元单细胞亚群划分主要是靠转录因子 以上绝大部分研究都是根据释放的神经递质对转化的神经元亚型进行区分,特别是谷氨酸能和 GABA 能神经元,它们分别是大脑中主要的兴奋性和抑制性神经元。 大多数 Neurog2 或 NeuroD1 转换的神经元是前脑谷氨酸能神经元,而 Ascl1 显示出 GABA 能神经元生成的趋势。 不同 …
TīmeklisNasopharyngeal carcinoma (NPC) is an Epstein-Barr virus-associated tumor prevalent in southern China and southeast Asia, with the 3p14-p12 locus reported as a critical tumor suppressor gene (TSG) region during its pathogenesis. We identified a novel 3p14.2 TSG, FEZF2 (FEZ family zinc finger 2), for …
Tīmeklis2024. gada 11. jūn. · 如果简单的说,就是, 使得突触后神经元放电率提高的突触前神经元就是兴奋性神经元,反之——使得突触后神经元放电率降低的突触前神经元就是抑制性神经元。. 兴奋性与抑制性神经元的分类不是绝对的,主要看突触前神经元给突触后神经元带来的具体作用 ... Tīmeklis2024. gada 7. sept. · Figure 1.Lentiviral-mediated knockdown of Forebrain embryonic zinc finger 2 (Fezf2) in the mature motor cortex.(A) Male mice aged P21–25 were …
Tīmeklis2014. gada 15. okt. · To determine whether WT NSCs change fate in fezf2 heterozygous or mutant environment, we performed reciprocal transplantation and analyzed the …
Tīmeklis2016. gada 1. marts · With a validated Fezf2-Gfp reporter mouse, whole-cell electrophysiology with morphology reconstruction, cluster analysis, in vivo retrograde … space coast health clinicTīmeklis2015. gada 6. nov. · Fezf2は胸腺の上皮細胞で、体の至るところで機能している遺伝子を発現させています。. 自己抗原が胸腺で作られることにより、それに反応するT細胞を選別し、除去できるのです。. Fezf2を持たない遺伝子改変マウスを調べたところ、自己抗体の産生や自己の ... teams equipment for conference roomsTīmeklis2024. gada 10. dec. · 作者使用Fezf2-CreER小鼠特异性地标记了位于岛叶皮层深层的一群神经元,并通过在体钙成像观察了这群神经元的钙活动变化。 他们发现很大比例的这群岛叶神经元参与编码动力,而与单纯的舔水管的动作无关。 进一步的光遗传抑制实验证实了这群神经元对于小鼠舔水的动力至关重要,而对舔水的动作并无影响。 那么这群 … teams eplaTīmeklis2024. gada 15. dec. · 当小鼠在做体力任务和认知任务时,该区域的一组激活Fezf2基因的神经元(下称Fezf2神经元)是活跃的。 Li和他的实验室假设,这些神经元并不影响 … teams e power appTīmeklis2015. gada 5. nov. · Here, we show that the transcription factor Fezf2 directly regulates various TRA genes in mTECs independently of Aire. Mice lacking Fezf2 in mTECs displayed severe autoimmune symptoms, including the production of autoantibodies and inflammatory cell infiltration targeted to peripheral organs. space coast health foundation rockledgeTīmeklis2024. gada 15. okt. · A new study identifies a novel population, defined by the molecular marker Fezf2, and demonstrates that two of its output pathways differentially encode … space coast home inspectionsTīmeklisWith a validated Fezf2-Gfp reporter mouse, whole-cell electrophysiology with morphology reconstruction, cluster analysis, in vivo retrograde labeling, and … space coast full throttle speedway