WebImmunoprecipitation analysis of GSDMD in 300 µg extracts of Jurkat cells using GSDMD Polyclonal Antibody (Product # PA5-116815). Western blot was performed from the immunoprecipitate using the same antibody at … WebFeb 9, 2024 · GSDMDC1 Antibody (64-Y) is an IgG 1 κ mouse monoclonal GSDMDC1 antibody (also designated GSDMDC1 antibody) suitable for the detection of the GSDMDC1 protein of human origin by WB, IP, IF, IHC(P) and ELISA. GSDMDC1 Antibody (64-Y) is available as the non-conjugated anti-GSDMDC1 antibody. The gene encoding …
Anti-cleaved N-terminal GSDMD antibody [EPR20829-408]
Web66387-1-Ig targets GSDMD in WB, IF, ELISA applications and shows reactivity with human samples. PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20°C. Stable for one year after shipment. … WebAll lanes : Anti-cleaved C-terminal GSDMD antibody [EPR20859-147] at 1/1000 dilution Lane 1 : iBMM (mouse immortalized bone marrow derived macrophages) treated with 500ng/ml Bsak plus 500ng/ml anthrax protective antigen (PA) for 2h. Cell lysate Lane 2 : iBMM (mouse immortalized bone marrow derived macrophages) treated with 500ng/ml … hotel near megamall mandaluyong
Anti-GSDMD Antibodies Invitrogen - Thermo Fisher …
WebMay 5, 2024 · Gasdermin-D (GSDMD) in inflammasome-activated macrophages is cleaved by caspase-1 to generate N-GSDMD fragments. N-GSDMD then oligomerizes in the plasma membrane (PM) to form pores that increase ... WebJul 7, 2016 · Inflammatory caspases (caspases 1, 4, 5 and 11) are activated in response to microbial infection and danger signals. When activated, they cleave mouse and human gasdermin D (GSDMD) after Asp276 and Asp275, respectively, to generate an N-terminal cleavage product (GSDMD-NT) that triggers inflammatory death (pyroptosis) and release … WebSep 16, 2015 · Caspase-1 can also cleave caspase-3/7 21, which may have a pyroptosis-independent function, particularly in the absence of GSDMD. Thus, the substrate cleaved by a caspase in a cellular context is ... hotel near masjid india kuala lumpur